News
Oxidative stress: Alternative utilization of glucose ensures survival of the cell
Oxidative stress in the cell blocks the normal sugar metabolism. Scientists from the German Cancer Research Center (DKFZ) and the team …
Welcome back Richard and Ulf!
In december, Richard Henchman and Ulf Hensen are visiting us to continue our work on entropy calculations. Welcome!
A new way to calculate conformational entropies!
Our joint paper with Ulf and Richard got accepted on how to calculate conformational entropies of complex molecules from molecular forces, …
FAK allosteric network helps interpreting FRET measurements!
Jing’s allosteric network of focal adhesion kinase (FAK) when binding PIP2 helped to interpret recent FRET results in FAK activation …
Welcome Katra!
Dr. Katra Kolsek joins us as a postdoc to work on disulfides in the von Willebrand factor. Welcome!
Welcome Ana!
We are happy that Ana Herrera Rodriguez joins us as a PhD student to work on silk assembly under flow. Welcome!
Mechanosensing ability of Focal Adhesion Kinase
Mechanosensing plays a decisive role at focal adhesions (Fas), sites at which external forces are integrated into cellular signaling pathways, thereby …
Composite Materials
Polymeric materials show outstanding mechanical properties and have attracted a great deal of scientific interest. By means of all-atom molecular dynamics, …
Focal Adhesion Kinase is a mechanosensor!
MD simulations of a FAK fragment containing the catalytic and FERM domains in different protein system are carried out to compare …
Proteins under shear flow
Shear flow, as it occurs for example in blood vessel, is an alternative way of subjecting proteins to forces for signalling …
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