Aktuelles
Oxidativer Stress: Alternative Zuckerverwertung sichert das Überleben der Zelle
Oxidativer Stress in der Zelle blockiert den normalen Zuckerstoffwechsel. Wissenschaftler im Deutschen Krebsforschungszentrum (DKFZ) und im Heidelberger Institut für Theoretische …
Welcome back Richard and Ulf!
In december, Richard Henchman and Ulf Hensen are visiting us to continue our work on entropy calculations. Welcome!
A new way to calculate conformational entropies!
Our joint paper with Ulf and Richard got accepted on how to calculate conformational entropies of complex molecules from molecular forces, …
FAK allosteric network helps interpreting FRET measurements!
Jing’s allosteric network of focal adhesion kinase (FAK) when binding PIP2 helped to interpret recent FRET results in FAK activation …
Welcome Katra!
Dr. Katra Kolsek joins us as a postdoc to work on disulfides in the von Willebrand factor. Welcome!
Welcome Ana!
We are happy that Ana Herrera Rodriguez joins us as a PhD student to work on silk assembly under flow. Welcome!
Mechanosensing ability of Focal Adhesion Kinase
Mechanosensing plays a decisive role at focal adhesions (Fas), sites at which external forces are integrated into cellular signaling pathways, thereby …
Composite Materials
Polymeric materials show outstanding mechanical properties and have attracted a great deal of scientific interest. By means of all-atom molecular dynamics, …
Focal Adhesion Kinase is a mechanosensor!
MD simulations of a FAK fragment containing the catalytic and FERM domains in different protein system are carried out to compare …
Small change for a big improvement – halogen bonds and drug discovery
Diese Informationen sind leider nur in englischer Sprache verfügbar. Halogen chemistry has been exploited by medicinal chemists for nearly 70 years. …