By Prof. Dr. Peter Hunter, Auckland Bioengineering Institute, University of Auckland, New Zealand Computational physiological models deal with multiple physical processes (coupled tissue mechanics, electrical activity, fluid flow, etc) at multiple spatial and temporal scales. In many cases the goal is to understand integrative biological function in terms of underlying tissue structure and molecular mechanisms. […]

By Prof. Dr. Richard A. Bonneau, Professor of Biology and Computer Science; Director, NYU Center for Data Science, New York, USA Vladimir Gligorijevic, P Douglas Renfrew and Richard Bonneau. Due to limitations of existing experimental methods for determining protein functions and the high cost of experiments, the vast majority of proteins across many organisms remain […]

Die Wahrheit, so scheint es, hat es schwer heutzutage: Oxford Dictionaries erklärte "post-truth" zum internationalen Wort des Jahres 2016; Fake News verbreiten sich oft schneller, als sie entlarvt werden können; und der Relotius-Skandal offenbarte Schwachstellen beim Faktencheck im deutschen Journalismus. Auch in der Wissenschaft gibt es Probleme: Wissenschaftliche Studien, etwa zur Ernährung, widersprechen sich allzu […]

By Nicholas G. Reich, Department of Biostatistics and Epidemiology, University of Massachusetts, School of Public Health and Health Sciences, Amherst, USA Seasonal influenza outbreaks cause substantial annual morbidity and mortality worldwide. Accurate forecasts of key features of influenza epidemics, such as the timing and severity of the peak incidence in a given season, can inform […]

By Keith A. Crandall, PhD, Professor ob Biostatistics & Bioinformatics, Director - Computational Biology Institute, Milken Institute School of Public Health, George Washington University, Washington, DC, USA   Microbiome characterization has become an integral component to the study of a wide variety of disease and health for a diversity of organisms. Through the collection of […]