HITS Researchers participate in a project that reveals the mechanism of molecular chaperones – Publication in Nature Structural & Molecular Biology
Together with researchers from Heidelberg University and the German Cancer Research Center DKFZ, Rebecca Wade and Mykhaylo Berynskyy (MCM group) revealed the functional mechanism of molecular chaperones, repair systems for aggregated proteins. Protein aggregation can lead to neurodegenerative diseases such as Alzheimer‘s or Parkinson‘s and plays a role in aging processes. The results were published in Nature Structural & Molecular Biology.
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HITS, the Heidelberg Institute for Theoretical Studies, was established in 2010 by physicist and SAP co-founder Klaus Tschira (1940-2015) and the Klaus Tschira Foundation as a private, non-profit research institute. HITS conducts basic research in the natural, mathematical, and computer sciences. Major research directions include complex simulations across scales, making sense of data, and enabling science via computational research. Application areas range from molecular biology to astrophysics. An essential characteristic of the Institute is interdisciplinarity, implemented in numerous cross-group and cross-disciplinary projects. The base funding of HITS is provided by the Klaus Tschira Foundation.
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