Colloquium Jens Meiler: Innovative Computational Methods for Protein Structure Prediction, Drug Discovery, and Therapeutic Design

Prof. Dr. Jens Meiler, Vanderbilt University, Informatics Center for Structural Biology, USA

Curriculum vitae: 

Jens Meiler studied Chemistry Leipzig University in Germany before he obtained his PhD working in the laboratory of Christian Griesinger at the Goethe University in Frankfurt developing new computational methods for biomolecular NMR spectroscopy. In 2001 he moved to Seattle to work with David Baker creating the protein modeling software Rosetta. In 2005 he joined the faculty at Vanderbilt University. In his research Dr. Meiler fuses computational and experimental efforts to investigate proteins, the fundamental molecules of biology, and their interactions with small molecule substrates, therapeutics, or probes. He develops computational methods with three major ambitions in mind: to enable protein structure elucidation of membrane proteins, design proteins with novel structure and/or function, and understand the relation between chemical structure and biological activity for drug-like small molecules. His research team in Nashville consists of around 30 undergraduate, graduate, and post-graduate students as well as staff scientists. He co-authored more than 200 peer-reviewed publications (H-index >40). Jens Meiler received several honors including the Chancellor Faculty Award at Vanderbilt University and the Friedrich-Wilhelm-Bessel Award of the Humboldt Foundation. In January 2020, with an Alexander von Humboldt Professorship, Jens Meiler became director of the newly founded Institute for Drug Discovery at Leipzig University.

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