Proteins under shear flow
Shear flow, as it occurs for example in blood vessel, is an alternative way of subjecting proteins to forces for signalling propagation nature is making use of. We are investigating how proteins react to the tensile forces occurring under high shear conditions, and how the resulting force sensing mechanisms balance protein function and misfunctions.
About HITS
HITS, the Heidelberg Institute for Theoretical Studies, was established in 2010 by physicist and SAP co-founder Klaus Tschira (1940-2015) and the Klaus Tschira Foundation as a private, non-profit research institute. HITS conducts basic research in the natural, mathematical, and computer sciences. Major research directions include complex simulations across scales, making sense of data, and enabling science via computational research. Application areas range from molecular biology to astrophysics. An essential characteristic of the Institute is interdisciplinarity, implemented in numerous cross-group and cross-disciplinary projects. The base funding of HITS is provided by the Klaus Tschira Foundation.
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