Dynamic disorder can explain non-exponential kinetics of fast protein mechanical unfolding
Dr. Bogdan Costescu et al. unfolded a protein in the computer thousands of times – and successfully detected signatures that hint towards fast but not too fast protein fluctuations that govern their unfolding times. See our invited article just published in a special issue on protein mechanics in the J. Struct. Biol. for more information
About HITS
HITS, the Heidelberg Institute for Theoretical Studies, was established in 2010 by physicist and SAP co-founder Klaus Tschira (1940-2015) and the Klaus Tschira Foundation as a private, non-profit research institute. HITS conducts basic research in the natural, mathematical, and computer sciences. Major research directions include complex simulations across scales, making sense of data, and enabling science via computational research. Application areas range from molecular biology to astrophysics. An essential characteristic of the Institute is interdisciplinarity, implemented in numerous cross-group and cross-disciplinary projects. The base funding of HITS is provided by the Klaus Tschira Foundation.
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